CVE-2025-12921

CVSS 4.3 Medium
  • CVSS Vector: CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N
  • Published: 2025-11-10T00:15:44.943

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

Related CVE by CWE

No related CWE found.

Top CVE for Vendor

No vendor taxonomy on this entry.

Recently Exploited Similar Vulnerabilities

No recent KEV-listed items for this vendor/product.

How to fix CVE-2025-12921

CVE-2025-12921 is a medium severity vulnerability affecting the affected product.

Description: A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the […]

Exploit Difficulty: EASY
⏱️ Time to exploit: < 1 hour
🛠️ Required skills: Basic web security knowledge
💰 Public exploits: Likely available

How to Fix:

1 Identify affected systems

- Check if you're running the affected product

2 Immediate actions

- Update to the latest patched version
- If patching is not immediately possible: restrict network exposure, apply least-privilege access

3 Verification

- Test the fix in a staging environment first
- Review logs for signs of exploitation
- Monitor for IOCs (Indicators of Compromise)

4 Long-term prevention

- Enable automatic security updates
- Set up vulnerability monitoring
- Review and harden security configurations

Exploit Difficulty Assessment

EASY
⏱️ Time to Exploit: < 1 hour
🛠️ Skills Required: Basic web security knowledge
💰 Public Exploits: Likely available

Vulnerability Timeline

Nov 10, 2025
Vulnerability Published

CVE details first published to NVD database

Nov 12, 2025
Imported to Database

Added to this CVE tracking system

Detection Rules & IOCs

No specific detection rules generated for this vulnerability type.

No vendor/product data available.

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